CSI Science Activities: Mystery-Based Investigations for Biology, Chemistry, Physics, and Earth Science

CSI science activities transform science review into a detective-style investigation where students must analyze evidence, identify misinformation, and uncover the truth.
In these investigations, a mysterious vandal has spread fake science throughout the city. If students cannot identify the incorrect information, the misinformation could spread forever.
Students must carefully evaluate evidence, apply scientific concepts, and work through clues to stop the vandal before science is ruined.
What are CSI Science Activities?
CSI science activities use a mystery-based structure to make science practice more engaging and meaningful.
Students work through a series of investigative tasks where each correct answer reveals new clues. As they analyze scientific statements, diagrams, and concepts, they narrow down the culprit responsible for spreading misinformation.
This structure keeps students motivated because every correct answer brings them closer to solving the case.
CSI Earth Science Activities
- The Earth’s Layers
- Plate Tectonics
- Minerals
- Rocks
- Renewable & Non-Renewable Resources
- Weathering
- Global Warming
- Natural Disasters
CSI Biology Activities
- Cell Theory & Structures
- Genetics
- Plant Structures
- Biomes
- Human Body Systems
- Brain
CSI Chemistry Activities
- States of Matter
- Atoms
- The Periodic Table
CSI Physics Activities
- Motion
- Speed, Velocity & Acceleration
- Energy
- Simple Machines
CSI Astronomy Activities
- Stars
- Milky Way Planets
Why Mystery-Based Science Activities Work
Mystery-based learning motivates students by giving them a clear objective: uncover the truth.
- Students stay engaged because they are solving a mystery
- Scientific reasoning becomes part of the investigation
- Collaboration naturally develops as students debate evidence
- Science review feels meaningful instead of repetitive
Explore More CSI Classroom Activities
These activities are part of our larger collection of CSI classroom activities, where students solve mysteries while practicing academic skills. Each subject uses a similar investigation format so students stay engaged while applying what they’ve learned.
If you’re new to the CSI series, start with the full overview here: CSI Classroom Activities.
You may also want to explore CSI activities in other subjects: